Antti Poso, Professor
Department of Pharmaceutical Chemistry
University of Eastern Finland, Kuopio Campus
PO Box 1627, FI-70211 Kuopio
Phone: +358-17-162-462
Fax: +358-17-162-456
Graduate students:
Piia Kokkonen
Dina Navia-Paldanius

The first research project is dealing with endocannabinoid system. The aim is to utilize molecular modeling methods, including 3D-QSAR, comparative protein modeling and database screening in designing new lead compounds active in the cannabinoid system, and especially for the CB1-receptor and FAAH-enzyme. The second research topic is in the field of virtual high-throughput screening. This so-called "In-Silico" project, partially funded by Tekes, is trying to develop a computerized method that uses molecular fields to measure similarity between molecules. Within the project new algorithms are developed which allow fast and accurate field alignment and comparison.