Vitaly Kochin

2.10.2009
Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Needles in a haystack: finding and characterizing protein phosphorylation sites that determine cellular decisions and functions

Reviewers:

Professor Carl G Gahmberg, Department of Biological and Environmental Sciences, University of Helsinki, Finland

Dr Nicholas Morrice, Protein Phosphorylation Unit, Medical Research Council, University if Dundee, United Kingdom

Opponent:

Professor Natalie G. Ahn, Department of Chemistry and Biochemistry, University of Colorado at Boulder, Colorado, USA

Publications:

  1. Kochin V, Imanishi SY, Eriksson JE. Fast track to a phosphoprotein sketch - MALDI-TOF characterization of TLC-based tryptic phosphopeptide maps at femtomolar detection sensitivity. Proteomics. 2006 Nov;6(21):5676-82.
  2. Imanishi SY, Kochin V, Eriksson JE. Optimization of phosphopeptide elution conditions in immobilized Fe(III) affinity chromatography. Proteomics. 2007 Jan;7(2):174-6.
  3. Imanishi SY, Kochin V, Ferraris SE, de Thonel A, Pallari HM, Corthals GL, Eriksson JE. Reference-facilitated phosphoproteomics: fast and reliable phosphopeptide validation by microLC-ESI-Q-TOF MS/MS. Mol Cell Proteomics. 2007 Aug;6(8):1380-91. Epub 2007 May 17
  4. Kochin V, Shimi T, Adam S, Goldman A, Nousiainen M, Koerner R, Goldman R, Eriksson JE. Mutations of phosphorylation sites in lamin A that affect nuclear lamina assembly and dynamics. (Manuscrpt)
  5. Kaunisto A, Kochin V, Asaoka T, Mikhailov A, Poukkula M, Meinander A, Eriksson JE. PKC-mediated phosphorylation regulates c-FLIP ubiquitylation and stability. Cell Death Differ. 2009 Sep;16(9):1215-26. Epub 2009 Apr 3.