Tarja Parkkinen

22.8.2008
Department of Chemistry, University of Joensuu, Joensuu

Structural Studies on Proteins with Industrial Potential: ENA11His Fab Fragment, Streptomyces rubiginosus Xylose Isomerase, Trichoderma reesei Xylanase IV and Melanocarpus albomyces Cellobiohydrolase

Reviewers:

Professor Reijo Lahti, University of Turku, Turku

Dr. Henrik Stålbrand, Lund University, Lund, Sweden

Opponent:

Docent Tuomo Glumoff, University of Oulu, Oulu

Custos:

Professor Juha Rouvinen, University of Joensuu, Joensuu

Publications:

  1. Parkkinen T, Nevanen T, Koivula A & Rouvinen J. (2006) Crystal structures of an enantioselective Fab and its complex with Finrozole. J Mol Biol. 357:471-480.
  2. Karimäki J, Parkkinen T, Santa S, Pastinen O, Leisola M, Rouvinen J & Turunen O. (2004) Engineering the substrate specificity of xylose isomerase. Prot. Eng. Des. Select. 17:861-869.
  3. Parkkinen T, Hakulinen N, Tenkanen M, Siika-aho M & Rouvinen J. (2004) Crystallization and preliminary X-ray analysis of a novel Trichoderma reesei xylanase IV belonging to glycoside hydrolase family 5. Acta Cryst D. 60:542-544.
  4. Parkkinen T, Koivula A, Vehmaanperä J & Rouvinen J. (2007) Preliminary X-ray analysis of cellobiohydrolase Cel7B from Melanocarpus albomyces. Acta Cryst F. 63:754-757.
  5. Parkkinen T, Koivula A, Vehmaanperä J & Rouvinen J. (2008) Crystal structures of Melanocarpus albomyces cellobiohydrolase Cel7B in complex with cello-oligomers show high flexibility in the substrate binding. Protein Sci. 17:1383-1394.