Tarja Parkkinen

Department of Chemistry, University of Joensuu, Joensuu

Structural Studies on Proteins with Industrial Potential: ENA11His Fab Fragment, Streptomyces rubiginosus Xylose Isomerase, Trichoderma reesei Xylanase IV and Melanocarpus albomyces Cellobiohydrolase


Professor Reijo Lahti, University of Turku, Turku

Dr. Henrik Stålbrand, Lund University, Lund, Sweden


Docent Tuomo Glumoff, University of Oulu, Oulu


Professor Juha Rouvinen, University of Joensuu, Joensuu


  1. Parkkinen T, Nevanen T, Koivula A & Rouvinen J. (2006) Crystal structures of an enantioselective Fab and its complex with Finrozole. J Mol Biol. 357:471-480.
  2. Karimäki J, Parkkinen T, Santa S, Pastinen O, Leisola M, Rouvinen J & Turunen O. (2004) Engineering the substrate specificity of xylose isomerase. Prot. Eng. Des. Select. 17:861-869.
  3. Parkkinen T, Hakulinen N, Tenkanen M, Siika-aho M & Rouvinen J. (2004) Crystallization and preliminary X-ray analysis of a novel Trichoderma reesei xylanase IV belonging to glycoside hydrolase family 5. Acta Cryst D. 60:542-544.
  4. Parkkinen T, Koivula A, Vehmaanperä J & Rouvinen J. (2007) Preliminary X-ray analysis of cellobiohydrolase Cel7B from Melanocarpus albomyces. Acta Cryst F. 63:754-757.
  5. Parkkinen T, Koivula A, Vehmaanperä J & Rouvinen J. (2008) Crystal structures of Melanocarpus albomyces cellobiohydrolase Cel7B in complex with cello-oligomers show high flexibility in the substrate binding. Protein Sci. 17:1383-1394.