Pekka Pohjanjoki

Department of Biochemistry and Food Chemistry, University of Turku, Turku

Functional Properties of Soluble Inorganic Pyrophosphatase from Saccharomyces Cerevisiae


Professor Inna Kuranova, Russian Academy of Sciences, Institute of Crystallography, Moscow, Russia

Professor Mark S. Johnson, Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku


Professor Alexander Vinogradov, Moscow State University, Russia


Professor Reijo Lahti, Department of Biochemistry, University of Turku, Turku


  1. Pohjanjoki P, Fabrichniy IP, Kasho VN, Goldman A, Cooperman BS, Baykov A & Lahti R. (2001) Probing Essential Water in Yeast Pyrophosphatase by Directed Mutagenesis and Fluoride Inhibition Measurements. J. Biol. Chem. 276(1):434-441.
  2. Belogurov GA, Fabrichniy IP, Kasho VN, Goldman A, Cooperman BS, Baykov AA & Lahti R. (2000) Catalyticaly Important Ionizations Along the Reaction Pathway of Yeast Pyrophosphatase. Biochemistry 39(45):13931-13938.
  3. Baykov AA, Fabrichniy IP, Pohjanjoki P, Zyryanov AB & Lahti R. (2000) Fluoride Effects along the Reaction Pathway of Yeast Pyrophosphatase: Evidence for a Second Enzyme Pyrophosphate Intermediate. Biochemistry 39(39):11939-11947.
  4. Pohjanjoki P, Lahti R, Goldman A & Cooperman BS. (1998) Evolutionary Conservation of Enzymatic Catalysis: Quantitative Comparison of the Effects of Mutation of Aligned Residues in Sasccharomyces cerevisiae and Escherichia coli Inorganic Pyrophosphatases on Enzymatic Activity. Biochemistry 37(7):1754-1761.
  5. Heikinheimo P, Pohjanjoki P, Helminen A, Tasanen M, Cooperman BS, Goldman A, Baykov A & Lahti R. (1996) A site-directed Mutagenesis Study of Saccharomyces cerevisiae Inorganic Pyrophosphatase. Functional conservation of the Active of Soluble Inorganic Pyrophosphatases. Eur. J. Biochem. 239(1):38-43.