Marko Tammenkoski

27.4.2007
Department of Biochemistry and Food Chemistry, University of Turku, Turku

One bond - many enzymes: Functional studies of three enzymes hydrolyzing the phosphoanhydride bond

Reviewers:

Professor J. Peter Slotte, Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Professor Rikkert Wierenga, Department of Biochemistry, University of Oulu, Oulu

Opponent:

Professor Aurelio Serrano, Institute of Plant Biochemistry and Photosynthesis, University of Sevilla, Sevilla, Spain

Custos:

Professor Reijo Lahti, Department of Biochemistry and Food Chemistry, University of Turku, Turku

Publications:

  1. Zyryanov AB, Tammenkoski M, Salminen A, Kolomiytseva GY, Fabrichniy IP, Goldman A, Lahti R & Baykov AA. (2004) Site-specific effects of Zinc on the Activity of Family II Pyrophosphatase. Biochemistry 43:14395-402.
  2. Halonen P, Tammenkoski M, Niiranen L, Huopalahti S, Parfenyev AN, Goldman A, Baykov A & Lahti R. (2005) Effects of active site mutations on the metal binding affinity, catalytic competence, and stability of the family II pyrophosphatase from Bacillus subtilis. Biochemistry 44:4004-10.
  3. Tammenkoski M, Benini S, Magretova NN, Baykov AA & Lahti R. (2005) An unusual, His-dependent family I pyrophosphatase from Mycobacterium tuberculosis. J. Biol. Chem. 280:41819-26.
  4. Tammenkoski M, Moiseev VM, Lahti M, Ugochukwu E, Brondijk TH, White SA, Lahti R & Baykov AA. (2007) Kinetic and mutational analyses of the major cytosolic exopolyphosphatase from Saccharomyces cerevisiae. J Biol Chem. 282:9302-11.