Konstantin Denessiouk

20.10.2000
Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Recognition of Adenine-containing Ligands, and Pyridoxyl-phosphate, by Proteins of Unrelated Tertiary Structure

Reviewers:

Professor Gunnar von Heijne, Department of Biochemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden

Professor Reijo Lahti, Department of Biochemistry, University of Turku, Turku

Opponent:

Professor Russell F. Doolittle, Department of Chemistry, University of California, San Diego, USA

Custos:

Professor Mark S. Johnson, Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Publications:

  1. Denessiouk KA, Lehtonen JV, Korpela T, Johnson MS. (1998) Two 'unrelated' families of ATP-dependent enzymes share extensive structural similarities about their cofactor binding sites. Protein Sci. 7:1136-1146.
  2. Denessiouk KA, Lehtonen JV, Johnson MS. (1998) Enzyme-mononucleotide interactions: three different folds share common structural elements for ATP recognition. Protein Sci. 7:1768-1771.
  3. Lehtonen JV, Denessiouk KA, May ACW, Johnson MS. (1999) Finding local structural similarities between families of unrelated protein structures: A generic non-linear alignment algorithm, Proteins: Struct. Funct. Genet. 34:341-355.
  4. Denessiouk KA, Denesyuk AI, Lehtonen JV, Korpela T, Johnson MS. (1999) Common structural elements in the architecture of the cofactor-binding domains in unrelated families of pyridoxal phosphate-dependent enzymes. Proteins: Struct. Funct. Genet. 35:250-261.
  5. Denessiouk K, Johnson MS. (2000) When fold is not important: A common structural framework for adenine and AMP binding in 12 unrelated protein families, Proteins: Struct. Funct. Genet. 38:310-326.
  6. Denessiouk KA, Rantanen V-V, & Johnson MS. (2001) Adenine recognition: a motif present in ATP-, CoA-, NAD-, NADP- and FAD-dependent proteins, Proteins: Struct. Funct. Genet. 44:282-91.