Kimmo Pääkkönen

Division of Biochemistry, Department of Biosciences, Faculty of Science, University of Helsinki, Finland

Application of residual dipolar couplings in structural studies of proteins



Professor Peter Güntert, RIKEN Genomic sciences center, Yokohama, Japan


Professor Carl G. Gahmberg, Department of Biosciences, Division of Biochemistiry, University of Helsinki, Finland


  1. Pääkkönen K, Annila A, Sorsa T, Pollesello P, Tilgmann C, Kilpeläinen I, Karisola P, Ulmanen I, Drakenberg T (1998) Solution structure and main chain dynamics of the regulatory domain (residues 1-91) of human cardiac troponin C. J. Biol.Chem. 273: 15633-15638.
  2. Pääkkönen K, Sorsa T, Drakenberg T, Pollesello P, Tilgmann C, Permi P, Heikkinen S, Kilpeläinen I, Annila A (2000) Conformations of the regulatory domain of cardiac troponin C examined by residual dipolar couplings. European Journal of Biochemistry 267: 6665-6672.
  3. Mattinen M, Pääkkönen K, Ikonen T, Craven J, Drakenberg T, Serimaa R, Waltho J, Annila A (2002) Quaternary structure built from subunits combining NMR and small-angle x-ray scattering data Biophys.J. 83: 1177 - 1183.
  4. Fredriksson K, Pääkkönen K, Louhivuori M, Permi P, Annila A (2003) On the origin of residual dipolar couplings from denatured proteins. JACS, submitted.