Johanna Jokinen

18.6.2010
Department of Biochemistry and Food Chemistry, University of Turku

Conformational Regulation of α2β1 Integrin in Ligand Binding

Reviewers:

Docent Peppi Karppinen, M.D., Ph.D., Department of Biochemistry and Molecular Biology, University of Oulu,Oulu, Finland

Docent Päivi Ojala Ph.D., Faculty of Medicine, University of Helsinki, Helsinki, Finland

Opponent:

Beate Eckes, Ph.D., Department of Dermatology, University of Cologne, Cologne, Germany

Custos:

Professor Jyrki Heino, Department of Biochemistry and Food Chemistry, University of Turku, Turku, Finland

Publications:

  1. Connors WL, Jokinen J, White DJ, Puranen JS, Kankaanpää P, Upla P, Tulla M, Johnson MS & Heino J (2007). Two synergistic activation mechanisms of alpha2beta1 integrin-mediated collagen binding. J Biol Chem.May 11;282(19):14675-83.
  2. Jokinen J, Dadu E, Nykvist P, Käpylä J, White DJ, Ivaska J, Vehviläinen P, Reunanen H, Larjava H, Häkkinen L & Heino J (2004). Integrin-mediated cell adhesion to type I collagen fibrils. J Biol Chem. Jul 23;279(30):31956-63
  3. Jokinen J, White DJ, Salmela M, Huhtala M, Käpylä J, Sipilä K, Puranen JS, Nissinen L, Kankaanpää P, Marjomäki V, Hyypiä T, Johnson MS & Heino J. (2010). Molecular mechanism of alpha2beta1 integrin interaction with human echovirus 1. EMBO J. Jan 6;29(1):196-208