Annu Söderholm

12.03.2010
Department of Biosciences, Åbo Akademi University

Computational Designs of Non-Steroidal Modulators of Androgen Receptor

Reviewers:

Professor C. Gopi Mohan, National Institute of Pharmaceutical Education and Research, Mohali, India

Dr. John P. Overington, European Bioinformatics Institute, Cambridge, United Kingdom

Opponent:

Opponent: Professor Antti Poso, Department of Pharmacy, University of Eastern Finland, Kuopio, Finland

Custos:

Professor Mark S. Johnson, Department of Biosciences, Åbo Akademi University

Publications:

  1. Söderholm AA, Lehtovuori PT, Nyrönen TH. (2005) Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain. J Med Chem. Feb 24;48(4):917-25.
  2. Söderholm AA, Lehtovuori PT, Nyrönen TH. Computational Detection of Non-Steroidal Androgen Receptor Ligands (Manuscript)
  3. Söderholm AA, Viiliäinen J, Lehtovuori PT, Eskelinen H, Roell D, Baniahmad A, Nyrönen TH. (2008) Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures. J Chem Inf Model. Sep;48(9):1882-90.
  4. Söderholm AA, Lehtovuori PT, Nyrönen TH. (2006) Docking and three-dimensional quantitative structure-activity relationship (3D QSAR) analyses of nonsteroidal progesterone receptor ligands. J Med Chem. Jul 13;49(14):4261-8.