National Doctoral Programme in
Informational and Structural Biology
Turku Centre for Biotechnology
University of Turku and Åbo Akademi University
PO Box 123, FI-20521 Turku
Phone: +358-2-333-8012
Fax: +358-2-333-8000
We use X-ray crystallography as a primary tool for the determination of the three-dimensional structures of proteins. Our main focus is on molecules involved in signalling pathways. Signalling is basically a problem of molecular recognition and protein-protein interactions. Our aim is to understand the structural aspects of this process at atomic level and to use the obtained structural information for the development of novel ways of therapeutic intervention in disease. In addition, we study enzyme stability and function in order to provide a better understanding of enzyme adaptation in extreme environmental conditions and to enable the design of better performance tailor-made enzymes in biotechnology.
We use X-ray crystallography as a primary tool for the determination of the three-dimensional structures of proteins. Our main focus is on molecules involved in signalling pathways. Signalling is basically a problem of molecular recognition and protein-protein interactions. Our aim is to understand the structural aspects of this process at atomic level and to use the obtained structural information for the development of novel ways of therapeutic intervention in disease. In addition, we study enzyme stability and function in order to provide a better understanding of enzyme adaptation in extreme environmental conditions and to enable the design of better performance tailor-made enzymes in biotechnology.