Publications 2000
- Aapola U, Kawasaki K, Scott HS, Ollila J, Vihinen M, Heino M, Shintani A,Kawasaki K, Minoshima S, Krohn K, Antonarakis SE, Shimizu N, Kudoh J & Peterson P. (2000) Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family. Genomics. 65(3):293-8.
- Aitio H & Permi P. (2000) Semi-constant-time HMSQC (SCT-HMSQC-HA) for the measurement of (3)J(H(N))(H(alpha)) couplings in (15)N-labeled proteins. J. Magn. Reson. 143(2):391-6.
- Baykov AA, Fabrichniy IP, Pohjanjoki P, Zyryanov AB & Lahti R. (2000) Flouride effects along the reaction pathway of pyrophosphatase. Evidence for a second enzyme-pyrophosphate intermediate. Biochemistry 39:11939-11947.
- Belogurov GA, Fabrichniy IP, Pohjanjoki P, Kasho V, Lehtihuhta E, Turkina MV, Cooperman BS, Goldman A, Baykov AA & Lahti R. (2000) Catalytically important ionizations along the reaction pathway of yeast pyrophosphatase. Biochemistry 39:13931-13938.
- Denesyuk AI, Denessiouk KA, Lehtonen JV, Korpela T, Johnson MS. (2000) Common structural elements in the architecture of the cofactor-binding domains in unrelated families of pyridoxal phosphate-dependent enzymes. In: Iriarte A, Kagan HM, Martinez-Carrion M (eds.) Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins, pp.123-128. Birkhäuser Verlag Basel, Switzerland.
- Denessiouk KD. (2000) Recognition of adenine containing ligands, and pyridoxyl-phosphate, by proteins of unrelated tertiary structure. Åbo Akademi University Press. (Dissertation).
- Denessiouk KD. (2000) Addendum. Recognition of adenine containing ligands, and pyridoxyl-phosphate, by proteins of unrelated tertiary structure. Åbo Akademi University Press. (Dissertation).
- Denessiouk K & Johnson MS. (2000) When fold is not important: A common structural framework for adenine and AMP binding in 13 unrelated protein families. Proteins: Struct. Funct. Genet. 38:310-326.
- Helaja J, Stapelbroek-Möllman M, Kilpeläinen I & Hynninen PH. (2000) NH tautomerism in the natural chlorine derivatives. J. Org. Chem. 65:3700-7.
- Jespersen LK, Kuusinen A, Orellana A, Keinänen K & Engberg J. (2000) Use of proteoliposomes to generate phage antibodies against native AMPA receptor. Eur. J. Biochem. 267:1382-1389.
- Johnson MS & Lehtonen JV. (2000) Comparisons of protein three-dimensional structures. In: Bioinformatics: A Practical Approach (Higgins & Taylor, Eds.) Oxford University Press. Chapter 2. pp. 15-50.
- Kapat A, Jaakola V-P, Heimo H, Liitti S, Heikinheimo P, Glumoff T & Goldman A. (2000) Production and purification of recombinant human alpha2C2 adrenergic receptor using Saccharomyces cerevisiae. Bioseparation 9:167-172.
- Kilpeläinen I, Kaksonen M., Kinnunen T, Raulo E, Avikainen H, Fath M, Linhardt R & Rauvala H. (2000) HB-GAM (heparin-binding growth associated molecule) contains two heparin-binding (-sheet domains that are homologous to the thrombospondin type I repeat. J. Biol. Chem. 275:13564-13570.
- Koivusalmi E, Hatanpää-Laitinen H, Haatainen E, Saarela T & Kilpeläinen I. (2000) Quantitative analysis of the components in synthesis mixtures of 2,2-dimethyl-3-hydroxypropionaldehyde by RP-HPLC and GC, Chromatographia, in press.
- Kuusinen A. (2000) Structure-function relations in AMPA receptors. Dissertationes Biocentri Viikki Universitatis Helsingiensis 4/2000. (Dissertation).
- Käpylä J, Ivaska J, Riikonen R, Nykvist P, Pentikäinen O, Johnson MS & Heino J. (2000) Integrin alpha2I domain recognizes type I and type IV collagens by different mechanisms. J. Biol. Chem. 275(05):3348-3354.
- Lampio A., Kilpeläinen I, Pesonen S, Karhi K, Auvinen P, Somerharju P & Kääriäinen L. (2000) Membrane-binding of Semliki Forest Virus mRNA capping enzyme - solution structure of the binding peptide and interaction with liposomes. J. Biol. Chem. 275:37853-37859.
- Levijoki J, Pollesello P, Kaivola J, Tilgmann C, Sorsa T, Annila A, Kilpeläinen I & Haikala H. (2000) Further evidence for the cardiac troponin C mediated calcium sensitization by levosimendan: structure-response and binding analysis with analogs of levosimendan. J. Mol. Cell Cardiol. 32(3):479-91.
- Mattsson PT, Lappalainen I, Bäckesjö C-M, Brockmann E, Lauren S, Vihinen M & Smith CIE. (2000) Six X-linked agammaglobulinemia-causing missense mutations in the Src 2 homology domain of Bruton's tyrosine kinase: Phosphotyrosine-binding and circular dichroism analysis. J. Immun. 164:4170-4177.
- Mattsson PT & Smith CIE. (2000) The Btk signaling pathway in B cell development. In: Proceedings of the IX meeting of the European Society for Immunodeficiencys, p.59-66, Ed. A. Etzioni, Monduzzi Editore, Italy.
- Nera K-P, Brockmann E, Vihinen M, Smith CIE & Mattsson PT. (2000) A rational design of human Bruton's tyrosine kinase SH3-SH2 protein purification and characteristics for structure-function studies. Protein Exp. Purific. 20:365-371.
- Nore BF, Vargas L, Mohammed AJ, Branden LJ, Bäckesjö C-M, Mattsson PT, Hultenby K, Christensson B & Smith CIE. (2000) Btk, a Tec family tyrosine kinase links phosphatidylinositol 3-kinase to small GTPases. Eur. J. Immunol. 30:145-154.
- Nyrönen T. (2000) Properties and Recognition Mechanisms of Molecules - Targeting Design of New Receptor Ligands. CSC Research Reports R01/2000. (Dissertation).
- Ohvo-Rekilä H, Åkerlund B & Slotte JP. (2000) Efflux of dehydroergosterol and cholestatrienol from unilamellar vesicles to 2-hydroxypropyl-ß-cyclodextrin - effects of phospholipid type and vesicle size on efflux kinetics. Chem. Phys. Lipids 105:167-178.
- Parfenyev AN, Salminen A, Baykov AA & Lahti R. (2000) Engineering a new magnesium binding site in the subunit contact region of Escherichia coli inorganic pyrophosphatase. Biochemistry (Moscow) 65:388-392.
- Permi P. (2000) Applications for measuring scalar and residual polar couplings in proteins. Acta Universitatis Ouluensis A354. (Dissertation).
- Permi P, Rosevear PR & Annila A. (2000) A set of HNCO-based experiments for measurement of residual dipolar couplings in 15N, 13C, (2H)-labeled proteins. J. Biomol. NMR. 17(1):43-54.
- Permi P & Annila A. (2000) Transverse relaxation optimised spin-state selective NMR experiments for measurement of residual dipolar couplings. J. Biomol. NMR. 16(3): 221-7.
- Permi P, Kilpeläinen I, and Annila A. (2000) Determination of backbone angle psi in proteins using a TROSY-based a/b-HN(CO)CA-J experiment. J. Magn. Reson. 146:255-259.
- Permi P, Kilpeläinen I, Annila A & Heikkinen S. (2000) Intensity modulated HSQC and HMQC: two simple methods to measure 3J(HNH)alpha in proteins. J. Biomol. NMR. 16(1):29-37.
- Pitkänen J, Doucas V, Sternsdorf T, Nakajima T, Aratani S, Jensen K, WillH, Vahamurto P, Ollila J, Vihinen M, Scott HS, Antonarakis SE, Kudoh J, Shimizu N, Krohn K, Peterson P. (2000) The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J. Biol. Chem. 275(22):16802-9.
- Pohjanjoki P. (2000) Functional properties of soluble inorganic pyrophosphatase from Saccharomyces cerevisiae, Annales Universitatis Turkuensis, Turun yliopisto (Dissertation).
- Ramstedt B & Slotte JP. (2000) Separation and purification of sphingomyelin diastereomers by high-performance liquid chromatography. Anal. Biochem., in press.
- Rauvala H, Huttunen HJ, Fages C, Kaksonen M, Kinnunen T, Imai S, Raulo E & Kilpeläinen I. (2000) Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility. Matrix Biology, in press.
- Vihinen M, Mattsson PT & Smith CIE. (2000) Bruton tyrosine kinase (Btk) in X-linked agammaglobulinemia. Frontiers in Bioscience 5:917-928.
- Wade D, Silberring J, Soliymani R, Heikkinen S, Kilpeläinen I, Lankinen H & Kuusela P. (2000) Antibacterial activities of temporin A analogs. FEBS Lett. 23875:1-4.
