Mauno Vihinen, Professor
Institute of Medical Technology
University of Tampere
PO Box 607, FI-33101 Tampere
Phone: +358-3-215-7735
Fax: +358-3-215-7710
Graduate students:
Juha J. Ollila
Gabriel Ndipagbornchi Teku

The experimental work in the group is devoted to studies on signal transduction, specifically immunodeficiency related Bruton tyrosine kinase (Btk). To generate experimental information to be further tested with bioinformatics, we are studying e.g. three-dimensional structure of Btk, specificity of its domains, disease-causing mutations and their mechanims. All these studies rely heavily on the use of computational analyses and on the development of computer tools to perform the analyses and predictions.

The research group consists of two post-doctoral fellows (one in crystallography and one in molecular modelling), and of eight research scientists/graduate students plus a system manager and Web-manager. The members of the team have diverse backgrounds, which is a prerequisite for a multidisciplinary research group. The team works closely together and supports the research of each member.