Juha Rouvinen, Professor
Department of Chemistry
University of Eastern Finland, Joensuu Campus
PO Box 111, FI-80101 Joensuu
Phone: +358-13-251-3318
Fax: +358-13-251-3390
Graduate students:
Mikko Purmonen
Mohammed Mubinur Rahman
Helena Taberman

The focus of our research has been on the wood degrading enzymes (xylanases, cellulases, acetyl xylan esterases, and laccases). One strong research area has been Fab-fragments of IgG antibodies. We have determined several structures of testosterone-binding Fab-fragments. In addition, we have determined medically important protein structures, for example the crystal structure of human lysosomal aspartylglucosaminidase. The mutation in the gene encoding for this enzyme may cause a several disease called aspartylglucosaminuria which may results in mental retardation. We have determined the structure of major bovine allergen Bos d 2, and we have just started a new research project in order to determine the crystal structure of Alzheimer amyloid precursor protein.