Salla Ruskamo

14.01.2011
Department of Biologial and Envirmonmental Sciences, University of Jyväskylä, Jyväskylä, Finland

Structures, interactions and packing of filamin domains

Reviewers:

Docent Pirta Hotulainen, Neuroscience Center, University of Helsinki, Helsinki, Finland

Docent Tiina Salminen Department of Biosciences, Åbo Akademi University, Turku, Finland

Opponent:

Docent Petri Kursula, Department of Biochemistry, University of Oulu, Oulu, Finland

Custos:

Professor Jari Ylänne, Department of Biologial and Envirmonmental Sciences, University of Jyväskylä, Jyväskylä, Finland

Publications:

  1. Ruskamo S, Ylänne J.(2009) Structure of the human filamin A actin-binding domain. Acta Crystallogr D Biol Crystallogr. 65:1217-1221.
  2. Lad Y*, Jiang P*, Ruskamo S*, Harburger DS, Ylänne J, Campbell ID, Calderwood DA. (2008) Structural basis of the migfilin-filamin interaction and competition with integrin beta tails. J Biol Chem.Dec 12;283(50): 35154-63.
  3. Heikkinen OK, Ruskamo S, Konarev PV, Svergun DI, Iivanainen T, Heikkinen SM, Permi P, Koskela H, Kilpeläinen I, Ylänne J. (2009) Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin. J Biol Chem. 11; 284(37): 25450-8.
  4. Ruskamo S, Ylänne J & Pentiäinen U Filamin domain assembly regulates its C terminal interactions: Structure and flexibilyt of six domain fragment (manuscript).
* Equal contribution