Pekka Pohjanjoki

22.9.2000
Department of Biochemistry and Food Chemistry, University of Turku, Turku

Functional Properties of Soluble Inorganic Pyrophosphatase from Saccharomyces Cerevisiae

Reviewers:

Professor Inna Kuranova, Russian Academy of Sciences, Institute of Crystallography, Moscow, Russia

Professor Mark S. Johnson, Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Opponent:

Professor Alexander Vinogradov, Moscow State University, Russia

Custos:

Professor Reijo Lahti, Department of Biochemistry, University of Turku, Turku

Publications:

  1. Pohjanjoki P, Fabrichniy IP, Kasho VN, Goldman A, Cooperman BS, Baykov A & Lahti R. (2001) Probing Essential Water in Yeast Pyrophosphatase by Directed Mutagenesis and Fluoride Inhibition Measurements. J. Biol. Chem. 276(1):434-441.
  2. Belogurov GA, Fabrichniy IP, Kasho VN, Goldman A, Cooperman BS, Baykov AA & Lahti R. (2000) Catalyticaly Important Ionizations Along the Reaction Pathway of Yeast Pyrophosphatase. Biochemistry 39(45):13931-13938.
  3. Baykov AA, Fabrichniy IP, Pohjanjoki P, Zyryanov AB & Lahti R. (2000) Fluoride Effects along the Reaction Pathway of Yeast Pyrophosphatase: Evidence for a Second Enzyme Pyrophosphate Intermediate. Biochemistry 39(39):11939-11947.
  4. Pohjanjoki P, Lahti R, Goldman A & Cooperman BS. (1998) Evolutionary Conservation of Enzymatic Catalysis: Quantitative Comparison of the Effects of Mutation of Aligned Residues in Sasccharomyces cerevisiae and Escherichia coli Inorganic Pyrophosphatases on Enzymatic Activity. Biochemistry 37(7):1754-1761.
  5. Heikinheimo P, Pohjanjoki P, Helminen A, Tasanen M, Cooperman BS, Goldman A, Baykov A & Lahti R. (1996) A site-directed Mutagenesis Study of Saccharomyces cerevisiae Inorganic Pyrophosphatase. Functional conservation of the Active of Soluble Inorganic Pyrophosphatases. Eur. J. Biochem. 239(1):38-43.