Mikko Ylilauri

24.01.2014
Department of Biological and Environmental Science, University of Jyväskylä

Effect of ligand-binding on protein function

Reviewers:

Associate Professor Georffrey Swanson, Molecular Pharmacology and Biological Chemistry, Northwestern University, Feinberg School of Medicine, Chicago, USA

Associate Professor Mikael Peräkylä, department of Pharmacy, University of Eastern Finland, Kuopio, Finland

Opponent:

Philip Biggin, Department of Pharmacy, University of Oxford, Oxford, United Kingdom

Custos:

Adjunct Professor Olli Pentikäinen, Department of Biological and Environmental Science, University of Jyväskylä

Publications:

  1. Postila PA, Ylilauri M, Pentikäinen OT (2011) Full and partial agonism of ionotropic glutamate receptors indicated by molecular dynamics simulations. J Chem Inf Model. 51(5):1037-47
  2. Ylilauri M, Pentikäinen OT (2012) Structural mechanism of N-methyl-D-aspartate receptor type 1 partial agonism. PLoS One. 2012;7(10):e47604
  3. Ylilauri M, Pentikäinen OT (2013) MMGBSA as a tool to understand the binding affinities of filamin-peptide interactions. J Chem Inf Model. 53(10):2626-33
  4. Ylilauri M, Mattila E, Nurminen EM, Käpylä J, Niinivehmas SP, Määttä JA, Pentikäinen U, Ivaska J, Pentikäinen OT (2013) Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone. Biochim Biophys Acta. 1834(10):1988-97