Kimmo Pääkkönen

19.9.2003
Division of Biochemistry, Department of Biosciences, Faculty of Science, University of Helsinki, Finland

Application of residual dipolar couplings in structural studies of proteins

Reviewers:

Opponent:

Professor Peter Güntert, RIKEN Genomic sciences center, Yokohama, Japan

Custos:

Professor Carl G. Gahmberg, Department of Biosciences, Division of Biochemistiry, University of Helsinki, Finland

Publications:

  1. Pääkkönen K, Annila A, Sorsa T, Pollesello P, Tilgmann C, Kilpeläinen I, Karisola P, Ulmanen I, Drakenberg T (1998) Solution structure and main chain dynamics of the regulatory domain (residues 1-91) of human cardiac troponin C. J. Biol.Chem. 273: 15633-15638.
  2. Pääkkönen K, Sorsa T, Drakenberg T, Pollesello P, Tilgmann C, Permi P, Heikkinen S, Kilpeläinen I, Annila A (2000) Conformations of the regulatory domain of cardiac troponin C examined by residual dipolar couplings. European Journal of Biochemistry 267: 6665-6672.
  3. Mattinen M, Pääkkönen K, Ikonen T, Craven J, Drakenberg T, Serimaa R, Waltho J, Annila A (2002) Quaternary structure built from subunits combining NMR and small-angle x-ray scattering data Biophys.J. 83: 1177 - 1183.
  4. Fredriksson K, Pääkkönen K, Louhivuori M, Permi P, Annila A (2003) On the origin of residual dipolar couplings from denatured proteins. JACS, submitted.