Jukka Lehtonen

26.11.2004
Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Development of computational methods for analysis and visualization of biomolecules and their complexes

Reviewers:

Professor Tapio Salakoski, Department of Information Technology, University of Turku, Turku

Dr. Catherine Murray, Glasgow, UK

Opponent:

Professor Inge Jonassen, Department of Informatics and Computational Biology Unit, Bergen Centre for Computational Science, University of Bergen, Bergen, Norway.

Custos:

Professor Mark S. Johnson, Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Publications:

  1. Lehtonen JV, Denessiouk KA, May ACW & Johnson MS. (1999) Finding local structural similarities among families of unrelated protein structures: A generic non-linear algorithm. Proteins: Struct. Funct. Genet. 34 (3):341-355.
  2. Denessiouk KA, Lehtonen JV, Korpela T & Johnson MS. (1998) Two "unrelated" families of ATP-dependent enzymes share extensive structural similarities about their cofactor binding sites. Protein Sci. 7:1136-1146.
  3. Denessiouk KA, Lehtonen JV & Johnson MS (1998) Enzyme-mononucleotide interactions: three different folds share common structural elements for ATP recognition. Protein Sci. 7:1768-1771.
  4. Lehtonen JV, Still D-J, Rantanen V-V, Ekholm J, Björklund D, Iftikhar Z, Huhtala M, Repo S, Jussila A, Jaakkola J, Pentikäinen O, Nyrönen T, Salminen T, Gyllenberg M & Johnson MS. (2004) BODIL: a molecular modeling environment for structure-function analysis and drug design. J Comp. Aided Molec. Des. (accepted).
    Bodil molecular modeling platform, Computer program, available from: http://www.abo.fi/bodil
  5. Nymalm Y, Kravchuk Z, Salminen T, Chumanevich A, Dubnovitsky A, Kankare J, Pentikäinen O, Lehtonen J, Arosio P, Martsev S & Johnson M. (2002) Antiferritin VL homodimer binds human spleen ferritin with high specificity. J Struct Biol. 138:171-186.