Juha Huiskonen

16.12.2005
Institute of Biotechnology, University of Helsinki, Helsinki

Structure and assembly of membrane-containing dsDNA bacteriophages

Reviewers:

Professor Mark S. Johnson, Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku

Doctor Jonathan M. Grimes, Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, UK

Opponent:

Dr. Tony Crowther, MRC Laboratory of Molecular Biology, Cambridge, UK

Custos:

Professor Tapio Palva, Department of Biological and Environmental Sciences, Division of Genetics, University of Helsinki

Publications:

  1. San Martín C, Huiskonen JT, Bamford JK, Butcher SJ, Fuller SD, Bamford DH & Burnett RM. (2002) Minor proteins, mobile arms and membrane-capsid interactions in the bacteriophage PRD1 capsid. Nat Struct Biol. 9:756-763.
  2. Huiskonen JT, Kivelä HM, Bamford DH & Butcher SJ. (2004) The PM2 virion has a novel organization with an internal membrane and pentameric receptor binding spikes. Nat Struct Mol Biol. 11:850-856.
  3. Merckel MC, Huiskonen JT, Bamford DH, Goldman A & Tuma R. (2005) The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture. Mol Cell. 18:161-170.
  4. Laurinmäki PA*, Huiskonen JT*, Bamford DH & Butcher SJ. (2005) Membrane proteins modulate the bilayer curvature in the bacterial virus Bam35. Structure. 13:1819-1828.

    * These authors contributed equally.