Jarkko Koivunen

19.08.2011
Nanoscience Center, Department of Biological and Environmental Science, University of Jyväskylä

Discovery of α2β1 integrin ligands: Tools and drug candidates for cancer and thrombus

Reviewers:

Adjunct professor, PhD Tommi Nyrönen, CSC -IT Center for Science Ltd., Espoo, Finland

Adjunct professor, PhD, Tapio Nevalainen School of Pharmacy, University of Eastern Finland, Kuopio, Finland

Opponent:

Adjunct Professor, PhD, Tiina Salminen, Department of Biosciences, Åbo Akademi University, Turku

Custos:

Adjunct Professor Olli Pentikäinen, Department of Biological and Environmental Science, University of Jyväskylä

Publications:

  1. Koivunen JT, Nissinen L, Juhakoski A, Pihlavisto M, Marjamäki A, Huuskonen J, Pentikäinen OT. (2011) Blockage of Collagen Binding to Integrin α2β1: Structure-activity Relationship of Protein-protein Interaction Inhibitors. MedChemComm (in press)
  2. Koivunen JT, Nissinen L, Käpylä J, Pihlavisto M, Heino J, Marjamäki A, Huuskonen J, Pentikäinen OT (2011) Fluorescent probe to modulate and explore α2β1 integrin function. (Submitted)
  3. Korhonen J, Marjamäki A, Nissinen L, Pihlavisto M, pentikäinen OT, Koivunen JT (2010) Urea substituted sulphonamide derivates. Patent appliction: WO/2010/146236
  4. Nissinen L, Koivunen JT, Käpylä J, Nieminen J, Jokinen J, Sipilä K, Pihlavisto M, Pentikäinen OT, Marjamäki A, Heino J (2011) Under shear stress &alpha2β1 intergrin binding to collagen does not require receptor pre-activation. (Submitted)