Annamari Paino
10.01.2014
Department of Biochemistry, University of Turku
Virulence properties of Aggregatibacter actinomycetemcomitans biofilm
and characterisation of its putative cytokine exploitation
Reviewers:
Associate Professor Georgios Belibasakis, DDS, Ph.D. Section of Oral Microbiology and Immunology, Institute of Oral Biology University of Zurich, Switzerland
Docent Pirkko Pussinen, Ph.D., Institute of Dentistry, University of Helsinki, Helsinki, Finland
Opponent:
Professor Mikael Rhen, Ph.D. Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Sweden
Supervised by
Docent Riikka Ihalin, Ph.D. Department of Biochemistry, University of Turku, Turku, Finland
Marja Pöllänen, DDS, Ph.D. Department of Periodontology, Institute of Dentistry University of Turku, Turku, Finland
Custos:
Professor Jyrki Heino, Department of Biochemistry, University of Turku, Turku, Finland
Publications:
- Paino A, Tuominen H, Jääskeläinen M, Alanko J, Nuutila J, Asikainen
SE, Pelliniemi LJ, Pöllänen MT, Chen C, Ihalin R. (2011) Trimeric form
of intracellular ATP synthase subunit β of Aggregatibacter
actinomycetemcomitans binds human interleukin-1β. PLoS One.
6(4):e18929.
- Paino A, Lohermaa E, Sormunen R, Tuominen H, Korhonen J, Pöllänen
MT, Ihalin R. (2012) Interleukin-1β is internalised by viable
Aggregatibacter actinomycetemcomitans biofilm and locates to the outer
edges of nucleoids. Cytokine. 60(2):565-74
- Paino A, Ahlstrand T, Nuutila J, Navickaite I, Lahti M, Tuominen
H, Välimaa H, Lamminmäki U, Pöllänen MT, Ihalin R. (2013)
Identification of a novel bacterial outer membrane
interleukin-1Β-binding protein from Aggregatibacter
actinomycetemcomitans. PLoS One. 8(7):e70509
- Tarry M, Jääskeläinen M, Paino A, Tuominen H, Ihalin R, Högbom M. (2011)
The extra-membranous domains of the competence protein HofQ show DNA
binding, flexibility and a shared fold with type I KH domains. J Mol
Biol. 409(4):642-53