Theses

Doctor of Philosophy (PhD) and Master of Science (MSc) theses completed in the laboratory.

PhD

  • Denessiouk, Konstantin (2000) Recognition of adenine-containing ligands, and pyridoxyl phosphate, by proteins of unrelated tertiary structure.
  • Kidron, Heidi (2006) Structure-based predictions of enzyme function
  • Lehtonen, Jukka (2004) Development of computational methods for analysis and visualization of biomolecules and their complexes.
  • Nymalm, Yvonne (2004) Structural basis of protein function: integrin alpha1I, vascular adhesion protein 1 and the VL domain of the antiferritin antibody.
  • Nyrönen, Tommi (2000) Properties and recognition mechanisms of molecules - targeting design of new receptor ligands.
  • Pentikäinen, Olli (2003) Modeling of protein-ligand interactions: Integrin I-domains and ionotropic glutamate receptors.
  • Puranen, Santeri (2010) Electrostatics in Molecular Modeling.
  • Rantanen, Ville-Veikko (2004) (University of Turku) Mathematical modeling of molecular interactions.
  • Repo, Susanna (2008) Structural bioinformatics in the study of protein function and evolution.
  • Settimo, Luca (2005) Structural basis for ligand recognition in the ionotropic glutamate receptors.
  • Vainio, Mikko (2008) Chemoinformatics in Targeted Drug Design.
  • Viitanen, Lenita (2010) Structural Features of Ligand Binding: Sterol Carrier Protein-2 and Glycolipid Transfer Protein.
  • Xhaard, Henri (2006) Adrenoceptors: Evolution, structure modeling and ligand recognition.

MSc

  • Barman, Hanna (2003) X-ray structure and determination of integrin alpha1 and alpha2 domains in complex with inhibitors.
  • Boucht, Camilla (2005) Homologimodellering av det polymorfa cytokrom P450 2D6 enzymet.
  • Chesnel, Delphine (2005) (University of Innsbruck) Structural analysis and modeling of arginine decarboxylases from Synechocystis sp. PCC6803, Arabidopsis Thaliana and human.
  • Eerola, Kim (2007) Characterization of the splice variants of interleukin-6.
  • Forss, Sonja (2002) Dockningsstudier av småmolekylära ligander till cyclodextriner.
  • Hokkanen, Annika (2008) Strukturella studier av de två besläktade proteinerna vaskulärt adhesionsprotein-1 och retinaspecifikt aminoxidas.
  • Huhtala, Mikko (2000) (University of Turku) Design of selective serine protease inhibitors. Structural studies and phylogenetic analysis of human kallikreins.
  • Kidron, Heidi (2001) Proteinrening och kristallisering av integrin alpha10-I-domän.
  • Lindholm, Pamela (2003) Unveckling av nya konstrukt för produktion och kristallisering av integrin alfa10 och alfa11 I-domän.
  • Mikkola, Nina (2005) Expression och rening av Synechocystis karboxyterminalt protease A.
  • Moretti, Loris (2002) (University of Padova) Molecular recognition in NMDA receptor, subunit NR1, exploiting published experimental data through molecular modeling.
  • Nymalm, Yvonne (1999) Proteinrening och kristallisering av integrin alpha1-I-domän.
  • Puranen, Santeri (2002) Structural comparison of the ligand-binding sites in integrin I-domains.
  • Repo, Susanna (2002) Modeling and structural comparison of the ligand-binding domains of the estrogen receptor-related receptors.
  • Rossato, Gianluca (2008) (University of Padova) Comparative modeling of dopamine, norepinephrine and serotonin transporters in complex with tricyclic antidepressants.
  • Söderholm, Annu (2003) Structural studies on copper-containing amine oxidases: Crystallization of human vascular adhesion protein-1 (HVAP-1) and homology modeling of human diamine oxidase (HDAO).
  • Varis, Minna (2002) Structure and function of alpha-adrenergic receptor 2A.
  • Viitanen, Lenita (2002) Kristallisering av alpha2 I-domän som complex med småmolekylära inhibitorer av kollagenbinding.